This workshop delves into how estrogen decline during menopause drives lower urinary tract symptoms, including overactive bladder. Explore the molecular role of estrogen, its receptor targets, and their impact on bladder function. Attendees will learn to categorize and distinguish OAB subtypes using flowcharts and key patient questions. The session covers lifestyle strategies, current treatment limitations, and introduces Jude's novel approach to addressing unmet clinical needs for LUTS management.